منابع مشابه
Thiazide diuretics in hypertension
Authors: Ferreira R. The use of diuretics (and beta-blockers) to treat hypertension has known a dramatic decline since the early 1980’s through to the early 1990s with the introduction of ACE-inhibitors and calcium channel blockers. However, thiazide diuretics are still a first line option to treat arterial hypertension, due to their efficacy and cost-effectiveness profile. We have presented ma...
متن کاملDiuretics in the treatment of hypertension. Part 1: thiazide and thiazide-like diuretics.
INTRODUCTION Thiazides and thiazide-like diuretics inhibit the electroneutral Na(+)-Cl(-) cotransporter located on the apical membrane of the early segment of the distal convoluted tubule. They have been widely prescribed over 60 years in the treatment of hypertension and various edematous states. AREAS COVERED Thiazide diuretics reduce blood pressure (BP), although the mechanisms by which th...
متن کاملComparison of thiazide‐like diuretics versus thiazide‐type diuretics: a meta‐analysis
Thiazide diuretics are widely used for the management of hypertension. In recent years, it has been actively debated that there is interchangeability of thiazide-type diuretics hydrochlorothiazide and thiazide-like diuretics including indapamide and chlorthalidone for the treatment of hypertension. With the purpose of seeking out the best thiazide diuretic for clinicians, we summarized the exis...
متن کاملThe cardiovascular risks of thiazide diuretics.
It is not surprising that a discipline as rapidly growing and changing as the management of hypertension should engender a number of controversies. These disagreements may have considerable medical, economic, and public health impact simply because there are so many millions of patients with hypertension involved. The purpose of this discussion is to present what some would consider controversi...
متن کاملPrimary hyperparathyroidism and thiazide diuretics.
Six patients receiving thiazide diuretics were referred for evaluation of mild to moderate hypercalcaemia (serum calcium 2.65-2.98 mmol/l). All patients were considered to be suffering from primary hyperparathyroidism. Withdrawal of the diuretic was followed by a reduction in the serum calcium, one patient becoming normocalcaemia. The mechanisms responsible for these changes are discussed. In h...
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ژورنال
عنوان ژورنال: Biopharmaceutics & Drug Disposition
سال: 1986
ISSN: 0142-2782,1099-081X
DOI: 10.1002/bdd.2510070602